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pentobarbital will lower the level or influence of tamoxifen by affecting hepatic enzyme CYP2C9/10 metabolism. Use Warning/Observe.pentobarbital will lower the level or effect of carvedilol by impacting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Check.pentobarbital will decrease the level or outcome of amlodipine by affecting hepatic/intestin